BDBM50089021 (8R,13R)-13-{[1-Acetyl-3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-6,14-dioxo-10,11-dithia-7,15-diaza-spiro[4.12]heptadecane-8-carboxylic acid::CHEMBL275603

SMILES CC(=O)N1CCC(C1C(=O)N[C@H]1CSSC[C@H](NC(=O)C2(CCCC2)CCNC1=O)C(O)=O)c1ccc(O)cc1

InChI Key InChIKey=VAZGXXMURSMRGV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089021   

TargetIntegrin alpha-4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089021((8R,13R)-13-{[1-Acetyl-3-(4-hydroxy-phenyl)-pyrrol...)
Affinity DataIC50: 0.100nMAssay Description:Compound was evaluated for VCAM-VLA-4 antagonistic activity using solid phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089021((8R,13R)-13-{[1-Acetyl-3-(4-hydroxy-phenyl)-pyrrol...)
Affinity DataIC50: 1.5nMAssay Description:Compound was evaluated for VCAM-VLA-4 antagonistic activity using Ramos cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed