BDBM50088876 1N-methyl-2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-1-ethanamine::CHEMBL170319

SMILES CNCCc1cn2C(C)CCc3cc(F)cc1c23

InChI Key InChIKey=SRHCSDYGKWADRG-UHFFFAOYSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50088876   

Target5-hydroxytryptamine receptor 2C(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088876(1N-methyl-2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrr...)
Affinity DataEC50:  180nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2C receptor expressed in HEK293 cells was determined using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088876(1N-methyl-2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrr...)
Affinity DataEC50:  1.10E+3nMAssay Description:Functional antagonist activity of compound was determined by fluorescence-based assay measuring intracellular calcium mobilization for 5-HT2a recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088876(1N-methyl-2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Functional agonist activity of compound was determined by fluorescence-based assay measuring intracellular calcium mobilization for 5-HT2a receptor c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088876(1N-methyl-2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrr...)
Affinity DataKi:  33nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2C receptor expressed in HEK293 cells was determined using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088876(1N-methyl-2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrr...)
Affinity DataKi:  1.46E+3nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2A receptor expressed in HEK293 cells was determined using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed