BDBM50088818 CHEMBL353978::Sodium; 3-methoxymethyl-5,5,8-trioxo-7-[1-pyridin-2-yl-meth-(Z)-ylidene]-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate

SMILES COCC1=C(N2C(\C(=C/c3ccccn3)C2=O)S(=O)(=O)C1)C([O-])=O

InChI Key InChIKey=KEDIJSGTHCTLIW-UHFFFAOYSA-M

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50088818   

TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088818(Sodium; 3-methoxymethyl-5,5,8-trioxo-7-[1-pyridin-...)
Affinity DataIC50: 700nMAssay Description:Inhibition of class C beta-lactamase derived from Enterobacter cloacae P99More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Staphylococcus aureus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088818(Sodium; 3-methoxymethyl-5,5,8-trioxo-7-[1-pyridin-...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of class A beta-lactamase derived from Staphylococcus aureus strain PC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088818(Sodium; 3-methoxymethyl-5,5,8-trioxo-7-[1-pyridin-...)
Affinity DataIC50: 700nMAssay Description:Inhibition of class A TEM-1 beta-lactamase derived from Enterobacter cloacaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088818(Sodium; 3-methoxymethyl-5,5,8-trioxo-7-[1-pyridin-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of GC1 extended spectrum class C beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed