BDBM50088709 4-[(1-Allyl-piperidin-4-yl)-phenyl-amino]-N,N-diethyl-benzamide::CHEMBL13403

SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CC=C)CC1)c1ccccc1

InChI Key InChIKey=WVHPNARCCSSMHR-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50088709   

TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50088709(4-[(1-Allyl-piperidin-4-yl)-phenyl-amino]-N,N-diet...)
Affinity DataEC50:  21nMAssay Description:Effective concentration against stimulation of [35S]GTP-gamma-S, binding in CHO cells transfected with the human opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50088709(4-[(1-Allyl-piperidin-4-yl)-phenyl-amino]-N,N-diet...)
Affinity DataKi:  24nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088709(4-[(1-Allyl-piperidin-4-yl)-phenyl-amino]-N,N-diet...)
Affinity DataKi:  24nMAssay Description:Inhibition of [3H]DPDPE radioligand binding to rat opioid receptor delta 1 site from rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088709(4-[(1-Allyl-piperidin-4-yl)-phenyl-amino]-N,N-diet...)
Affinity DataKi:  1.16E+3nMAssay Description:Binding affinity by inhibition of [3H]DAMGO binding to Opioid receptor mu 1 from rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50088709(4-[(1-Allyl-piperidin-4-yl)-phenyl-amino]-N,N-diet...)
Affinity DataKi:  1.16E+4nMAssay Description:Binding affinity for mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed