BDBM50088701 CHEMBL12364::N-(2-{4-[4-Fluoro-2-(2,2,2-trifluoro-ethoxy)-phenyl]-piperazin-1-yl}-ethyl)-2-(2-oxo-piperidin-1-yl)-acetamide

SMILES Fc1ccc(N2CCN(CCNC(=O)CN3CCCCC3=O)CC2)c(OCC(F)(F)F)c1

InChI Key InChIKey=HJDROFKHSGSZLZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50088701   

TargetAlpha-1A adrenergic receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088701(N-(2-{4-[4-Fluoro-2-(2,2,2-trifluoro-ethoxy)-pheny...)
Affinity DataKi:  129nMAssay Description:Binding affinity for human Alpha-1A adrenergic receptor expressed in COS cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088701(N-(2-{4-[4-Fluoro-2-(2,2,2-trifluoro-ethoxy)-pheny...)
Affinity DataKi:  5.35E+3nMAssay Description:Binding affinity for human Alpha-1D adrenergic receptor expressed in COS cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088701(N-(2-{4-[4-Fluoro-2-(2,2,2-trifluoro-ethoxy)-pheny...)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity for human Alpha-1B adrenergic receptor expressed in COS cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed