BDBM50088519 CHEMBL3526743

SMILES COc1ccc(cc1OC)S(=O)(=O)Nc1nc(c(CN)s1)-c1cccc(c1)[N+]([O-])=O

InChI Key InChIKey=IXIGNBSHCYBEDA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50088519   

TargetKynurenine 3-monooxygenase(Mouse)
Chdi Management/Chdi Foundation

Curated by ChEMBL
LigandPNGBDBM50088519(CHEMBL3526743)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of C57BL/6J mouse KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Chdi Management/Chdi Foundation

Curated by ChEMBL
LigandPNGBDBM50088519(CHEMBL3526743)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Chdi Management/Chdi Foundation

Curated by ChEMBL
LigandPNGBDBM50088519(CHEMBL3526743)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Wistar rat KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed