BDBM50088501 CHEMBL3526984

SMILES C[C@@H](N(C)C(=O)N1CC[C@@H](C[C@@H]1c1ccc(F)cc1C)N1CCN(C(O)C1)C(C)=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=IMIUKXZVUAUOBR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088501   

TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50088501(CHEMBL3526984)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using nifedipine substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50088501(CHEMBL3526984)
Affinity DataIC50: 8.22E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed