BDBM50088431 3-(Piperidin-3-yloxy)-pyridine::3-(piperidin-3-yloxy)pyridine::CHEMBL9965

SMILES C1CNCC(C1)Oc1cccnc1

InChI Key InChIKey=GHJPZQCAVQYABA-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50088431   

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088431(3-(piperidin-3-yloxy)pyridine | 3-(Piperidin-3-ylo...)
Affinity DataIC50: 191nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088431(3-(piperidin-3-yloxy)pyridine | 3-(Piperidin-3-ylo...)
Affinity DataEC50:  3.24E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088431(3-(piperidin-3-yloxy)pyridine | 3-(Piperidin-3-ylo...)
Affinity DataIC50: 204nMAssay Description:Evaluated for binding affinity towards nicotinic acetylcholine receptor alpha4-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed