BDBM50088297 CHEMBL3427748

SMILES NC(=O)C1CCCc2c1[nH]nc2-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=OQZPEYDZBJDMCK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50088297   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088297(CHEMBL3427748)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of His-tagged human recombinant SIRT2 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088297(CHEMBL3427748)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088297(CHEMBL3427748)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088297(CHEMBL3427748)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088297(CHEMBL3427748)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088297(CHEMBL3427748)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed