BDBM50088261 3,3,3',3'-tetramethyl-5,5',7'-trinitro-1,1'-spirobi[2,3-dihydro-1H-indene]-6,6'-diol::CHEMBL303764

SMILES CC1(C)CC2(CC(C)(C)c3cc(c(O)c(c23)[N+]([O-])=O)[N+]([O-])=O)c2cc(O)c(cc12)[N+]([O-])=O

InChI Key InChIKey=AEPFEKCKSRFWJD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50088261   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of California

Curated by ChEMBL
LigandPNGBDBM50088261(3,3,3',3'-tetramethyl-5,5',7'-trinitro-1,1'-spirob...)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of 3'-processing (TC) in the presence of Mn2+ in vitro More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of California

Curated by ChEMBL
LigandPNGBDBM50088261(3,3,3',3'-tetramethyl-5,5',7'-trinitro-1,1'-spirob...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of strand -transfer (ST) activity in the presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of California

Curated by ChEMBL
LigandPNGBDBM50088261(3,3,3',3'-tetramethyl-5,5',7'-trinitro-1,1'-spirob...)
Affinity DataIC50: 4.70E+4nMAssay Description:Tested in vitro against strand -transfer (ST) activity in the presence of Mg2+ as the cationic cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed