BDBM50088255 3,3,3',3'-tetramethyl-1,1'-spirobi[2,3-dihydro-1H-indene]-5,5',6,6'-tetraol::CHEMBL304266::HIV-1 Integrase Inhibitor

SMILES CC1(C)CC2(CC(C)(C)c3cc(O)c(O)cc23)c2cc(O)c(O)cc12

InChI Key InChIKey=POFMQEVZKZVAPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088255   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of California

Curated by ChEMBL
LigandPNGBDBM50088255(HIV-1 Integrase Inhibitor | 3,3,3',3'-tetramethyl-...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of 3'-processing (TC) in the presence of Mn2+ in vitro More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of California

Curated by ChEMBL
LigandPNGBDBM50088255(HIV-1 Integrase Inhibitor | 3,3,3',3'-tetramethyl-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of strand -transfer (ST) activity in the presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed