BDBM50088212 2-Amino-4-but-2-enyl-pentanedioic acid(LY339180)::CHEMBL294139

SMILES C\C=C\C[C@H](C[C@H](N)C(O)=O)C(O)=O

InChI Key InChIKey=SEHOBMVXPBLACF-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50088212   

TargetGlutamate receptor ionotropic, kainate 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088212(2-Amino-4-but-2-enyl-pentanedioic acid(LY339180) |...)
Affinity DataEC50:  4.50E+3nMAssay Description:Effective concentration required for evoking response in HEK293 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088212(2-Amino-4-but-2-enyl-pentanedioic acid(LY339180) |...)
Affinity DataEC50:  5.83E+4nMAssay Description:Effective concentration against human GluR6 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088212(2-Amino-4-but-2-enyl-pentanedioic acid(LY339180) |...)
Affinity DataKi:  21nMAssay Description:Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]kainate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50088212(2-Amino-4-but-2-enyl-pentanedioic acid(LY339180) |...)
Affinity DataKi:  3.26E+3nMAssay Description:Binding affinity against human ionotropic glutamate receptor ionotropic kainate 2 in HEK293 cells using [3H]kainate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed