BDBM50088089 CHEMBL55984::N-Hydroxy-2-[(4-nitro-benzyl)-(3-(N-(4-Fluoro-benzene)-sulfonyl)ureido-benzenesulfonyl)-amino]-acetamide

SMILES ONC(=O)CN(Cc1ccc(cc1)[N+]([O-])=O)S(=O)(=O)c1cccc(NC(=O)NS(=O)(=O)c2ccc(F)cc2)c1

InChI Key InChIKey=XCCIACQOXSWRJQ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50088089   

TargetNeutrophil collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50088089(N-Hydroxy-2-[(4-nitro-benzyl)-(3-(N-(4-Fluoro-benz...)
Affinity DataKi:  1.40nMAssay Description:Inhibitory activity against the Matrix Metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50088089(N-Hydroxy-2-[(4-nitro-benzyl)-(3-(N-(4-Fluoro-benz...)
Affinity DataKi:  1.80nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50088089(N-Hydroxy-2-[(4-nitro-benzyl)-(3-(N-(4-Fluoro-benz...)
Affinity DataKi:  2.5nMAssay Description:Inhibitory activity against the Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50088089(N-Hydroxy-2-[(4-nitro-benzyl)-(3-(N-(4-Fluoro-benz...)
Affinity DataKi:  17nMAssay Description:Inhibitory activity against the Clostridium histolyticum collagenase (ChC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50088089(N-Hydroxy-2-[(4-nitro-benzyl)-(3-(N-(4-Fluoro-benz...)
Affinity DataKi:  49nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed