BDBM50087695 8-Cyclohexyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL263575

SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)C1CCCCC1

InChI Key InChIKey=RKHMTVPPDQEMGU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087695   

TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087695(8-Cyclohexyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  25nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087695(8-Cyclohexyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  100nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087695(8-Cyclohexyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  158nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed