BDBM50087655 1,2-di{4-[4-(1-azepanyl)-1-pyridiniumylmethyl]phenyl}ethane dibromide::CHEMBL164952

SMILES C(Cc1ccc(Cn2ccc(cc2)=[N+]2CCCCCC2)cc1)c1ccc(Cn2ccc(cc2)=[N+]2CCCCCC2)cc1

InChI Key InChIKey=BODHLKVVDAHGHU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087655   

TargetCholine kinase alpha(Human)
Granada

Curated by ChEMBL
LigandPNGBDBM50087655(1,2-di{4-[4-(1-azepanyl)-1-pyridiniumylmethyl]phen...)
Affinity DataIC50: 1.50E+4nMAssay Description:Compound was tested ex vivo for inhibition against purified choline kinase obtained from yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50087655(1,2-di{4-[4-(1-azepanyl)-1-pyridiniumylmethyl]phen...)
Affinity DataIC50: 86nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50087655(1,2-di{4-[4-(1-azepanyl)-1-pyridiniumylmethyl]phen...)
Affinity DataIC50: 274nMAssay Description:Inhibition of equine BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed