BDBM50087436 2-(3,5-dihydroxystyryl)-8-hydroxyquinoline-7-carboxylic acid::2-[2-((E)-3,5-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quinoline-7-carboxylic acid::2-[2-(3,5-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quinoline-7-carboxylic acid::CHEMBL39958

SMILES OC(=O)c1ccc2ccc(\C=C\c3cc(O)cc(O)c3)nc2c1O

InChI Key InChIKey=WZCUUBHCFIUECD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50087436   

TargetIntegrase(Human immunodeficiency virus type 1)
Cnrs Umr 8076

Curated by ChEMBL
LigandPNGBDBM50087436(2-[2-((E)-3,5-Dihydroxy-phenyl)-vinyl]-8-hydroxy-q...)
Affinity DataIC50: 3.20E+3nMAssay Description:In vitro inhibition of recombinant integrase activity in a standard 3'-processing assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Cnrs Umr 8076

Curated by ChEMBL
LigandPNGBDBM50087436(2-[2-((E)-3,5-Dihydroxy-phenyl)-vinyl]-8-hydroxy-q...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory activity against Integrase in 3'-end- processingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Cnrs Umr 8076

Curated by ChEMBL
LigandPNGBDBM50087436(2-[2-((E)-3,5-Dihydroxy-phenyl)-vinyl]-8-hydroxy-q...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory activity against Integrase in strand transfer (integration)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50087436(2-[2-((E)-3,5-Dihydroxy-phenyl)-vinyl]-8-hydroxy-q...)
Affinity DataIC50: 400nMAssay Description:Inhibition of PIM1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50087436(2-[2-((E)-3,5-Dihydroxy-phenyl)-vinyl]-8-hydroxy-q...)
Affinity DataIC50: 3.24E+3nMAssay Description:Inhibition of HIV1 integrase 3' processing activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed