BDBM50087065 4-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-4-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butylcarbamoyl}-butyric acid (Ile5,6-Deltrophin II)::CHEMBL28915

SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)CC)C(=O)NCC(N)=O

InChI Key InChIKey=GNHBZJKRUQINTM-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50087065   

TargetDelta-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50087065(4-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: 3.10nMAssay Description:Displacement of [3H]Ile5,6deltorphin-2 from delta opioid receptor in Wistar rat brain membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50087065(4-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataKi:  0.390nMAssay Description:Binding affinities against delta 2 opioid receptor of rat brain using [3H]Ile5,6-deltorphin II as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50087065(4-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]Ile5,6deltorphin-2 from delta opioid receptor in Wistar rat brain membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50087065(4-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataKi:  3.19E+3nMAssay Description:Binding affinities against delta opioid receptor of rat brain using [3H]DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50087065(4-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed