BDBM50087037 1-Ethoxy-1-ethyl-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::CHEMBL281554

SMILES CCO[C@]1(CC)c2cccc3C[C@H]4N(C)CCc5ccc1c(-c23)c45

InChI Key InChIKey=IPMUUCRZGTZCPY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087037   

Target5-hydroxytryptamine receptor 1A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087037(1-Ethoxy-1-ethyl-6-methyl-1,5,5a,6,7,8-hexahydro-6...)
Affinity DataKi:  1.84nMAssay Description:Binding affinity was measured on cloned human 5-hydroxytryptamine 1A receptor which is labeled by [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087037(1-Ethoxy-1-ethyl-6-methyl-1,5,5a,6,7,8-hexahydro-6...)
Affinity DataKi:  25.7nMAssay Description:Displacement of [3H]5-HT from over-expressed rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087037(1-Ethoxy-1-ethyl-6-methyl-1,5,5a,6,7,8-hexahydro-6...)
Affinity DataKi:  70.8nMAssay Description:Displacement of [3H]raclopride from human Dopamine receptor D2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed