BDBM50086873 3-[1-(4-Fluoro-benzyl)-8-oxo-7,8-dihydro-1H-imidazo[4,5-g]quinazolin-6-yl]-4-propoxy-benzamide::CHEMBL278354

SMILES CCCOc1ccc(cc1-c1nc2cc3ncn(Cc4ccc(F)cc4)c3cc2c(=O)[nH]1)C(N)=O

InChI Key InChIKey=FHBUUNSHWMUODM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50086873   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50086873(3-[1-(4-Fluoro-benzyl)-8-oxo-7,8-dihydro-1H-imidaz...)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of phosphodiesterase type 5 (PDE5) of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50086873(3-[1-(4-Fluoro-benzyl)-8-oxo-7,8-dihydro-1H-imidaz...)
Affinity DataIC50: 0.480nMAssay Description:In vitro inhibitory concentration against human platelet Phosphodiesterase 5 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed