BDBM50086628 CHEMBL344688::Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-6-(3-methyl-isoxazol-5-ylcarbamoyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium;

SMILES Cc1cc(NC(=O)c2cc3c(OCCC4CCCC[NH2+]4)c(-c4cc(C)cc(C)c4)c(=O)[nH]c3cc2Cl)on1

InChI Key InChIKey=YPAPRBRATLYPAO-UHFFFAOYSA-O

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50086628   

TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086628(Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-ph...)
Affinity DataIC50: 23nMAssay Description:In vitro inhibitory activity against rat CHO cells stably expressing human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086628(Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-ph...)
Affinity DataIC50: 1.28E+3nMAssay Description:In vitro inhibitory activity against rat CHO cells stably expressing human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed