BDBM50086625 CHEMBL341717::Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-6-(3-methyl-isothiazol-5-ylcarbamoyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium;

SMILES Cc1cc(NC(=O)c2cc3c(OCCC4CCCC[NH2+]4)c(-c4cc(C)cc(C)c4)c(=O)[nH]c3cc2Cl)sn1

InChI Key InChIKey=LGWAVKYZALCEPM-UHFFFAOYSA-O

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50086625   

TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086625(Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-ph...)
Affinity DataIC50: 22nMAssay Description:In vitro inhibition of GnRH-stimulated phosphatidyl inositol hydrolysis in CHO cells stably expressing gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086625(Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-ph...)
Affinity DataIC50: 521nMAssay Description:In vitro inhibition of GnRH stimulated release of luteinizing hormone from the rat primary pituitary cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086625(Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-ph...)
Affinity DataIC50: 2.90nMAssay Description:In vitro inhibitory activity against rat CHO cells stably expressing human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed