BDBM50086620 CHEMBL138866::Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-6-(2-methyl-pyrimidin-4-ylcarbamoyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium;

SMILES Cc1cc(C)cc(c1)-c1c(OCCC2CCCC[NH2+]2)c2cc(C(=O)Nc3ccnc(C)n3)c(Cl)cc2[nH]c1=O

InChI Key InChIKey=LSWCHERKJUTYNF-UHFFFAOYSA-O

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50086620   

TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086620(Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-ph...)
Affinity DataIC50: 1.80nMAssay Description:In vitro inhibitory activity against rat CHO cells stably expressing human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086620(Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-ph...)
Affinity DataIC50: 1.80nMAssay Description:In vitro inhibitory activity against rat CHO cells stably expressing human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086620(Trifluoro-acetate2-{2-[7-chloro-3-(3,5-dimethyl-ph...)
Affinity DataIC50: 33nMAssay Description:In vitro inhibition of GnRH-stimulated phosphatidyl inositol hydrolysis in CHO cells stably expressing gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed