BDBM50086611 CHEMBL342908::Trifluoro-acetate2-{2-[7-chloro-6-(4-dimethylamino-phenylcarbamoyl)-3-(3,5-dimethyl-phenyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidinium;

SMILES CN(C)c1ccc(NC(=O)c2cc3c(OCCC4CCCC[NH2+]4)c(-c4cc(C)cc(C)c4)c(=O)[nH]c3cc2Cl)cc1

InChI Key InChIKey=SYARZNLXEFMJSC-UHFFFAOYSA-O

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50086611   

TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086611(Trifluoro-acetate2-{2-[7-chloro-6-(4-dimethylamino...)
Affinity DataIC50: 360nMAssay Description:In vitro inhibition of GnRH-stimulated phosphatidyl inositol hydrolysis in CHO cells stably expressing gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50086611(Trifluoro-acetate2-{2-[7-chloro-6-(4-dimethylamino...)
Affinity DataIC50: 360nMAssay Description:In vitro inhibition of GnRH-stimulated phosphatidyl inositol hydrolysis in CHO cells stably expressing gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed