BDBM50086477 1,3-Bis-(4-chloro-phenyl)-1,4,5,6-tetrahydro-cyclopentapyrazole::CHEMBL347945

SMILES Clc1ccc(cc1)-c1nn(c2CCCc12)-c1ccc(Cl)cc1

InChI Key InChIKey=GOUKFKRPAQNYGR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50086477   

TargetProstaglandin G/H synthase 1(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50086477(1,3-Bis-(4-chloro-phenyl)-1,4,5,6-tetrahydro-cyclo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human prostaglandin G/H synthase 1 in platelet-rich plasma measured by the presence of thromboxane A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50086477(1,3-Bis-(4-chloro-phenyl)-1,4,5,6-tetrahydro-cyclo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human prostaglandin G/H synthase 2 in ECV-304 cells measured by the presence of PGE-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed