BDBM50086340 4-Biphenyl-4-yl-1-methyl-piperidine-3-carboxylic acid methyl ester::CHEMBL20097

SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=HJCJROZGITWYJY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50086340   

TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50086340(4-Biphenyl-4-yl-1-methyl-piperidine-3-carboxylic a...)
Affinity DataKi:  62nMAssay Description:Inhibition of [3H]5-HT uptake by Serotonin transporter of rat midbrain or parietal synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50086340(4-Biphenyl-4-yl-1-methyl-piperidine-3-carboxylic a...)
Affinity DataKi:  173nMAssay Description:Inhibition of [3H]DA uptake by dopamine transporter of rat striata synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50086340(4-Biphenyl-4-yl-1-methyl-piperidine-3-carboxylic a...)
Affinity DataKi:  203nMAssay Description:Inhibition of [3H]NE uptake by Norepinephrine transporter of rat occipital cortex synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed