BDBM50086266 CHEMBL3425865

SMILES COc1cc(cc(OC)c1OC)-c1cnc2c(snc2c1)N1CCOCC1

InChI Key InChIKey=JONPTLGCLPUHKH-UHFFFAOYSA-N

Data  11 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50086266   

TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50086266(CHEMBL3425865)
Affinity DataKd:  8.30nMAssay Description:Binding affinity to human GAK fused to T7 bacteriophage expressed in Escherichia coli BL21 after 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50086266(CHEMBL3425865)
Affinity DataKd:  710nMAssay Description:Binding affinity to human CLK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
LigandPNGBDBM50086266(CHEMBL3425865)
Affinity DataKd:  320nMAssay Description:Binding affinity to human CSF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50086266(CHEMBL3425865)
Affinity DataKd:  110nMAssay Description:Binding affinity to human FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50086266(CHEMBL3425865)
Affinity DataKd:  29nMAssay Description:Binding affinity to human KITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
LigandPNGBDBM50086266(CHEMBL3425865)
Affinity DataKd:  150nMAssay Description:Binding affinity to human MEK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
LigandPNGBDBM50086266(CHEMBL3425865)
Affinity DataKd:  220nMAssay Description:Binding affinity to human PDGFRalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
LigandPNGBDBM50086266(CHEMBL3425865)
Affinity DataKd:  70nMAssay Description:Binding affinity to human PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50086266(CHEMBL3425865)
Affinity DataKd:  8.90nMAssay Description:Binding affinity to GAK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50086266(CHEMBL3425865)
Affinity DataKd:  8.30nMAssay Description:Binding affinity to GAK (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetCyclin-G-associated kinase(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50086266(CHEMBL3425865)
Affinity DataKd:  8.30nMAssay Description:Binding affinity to GAK (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed