BDBM50086173 CHEMBL17002::N-(4-Acetyl-phenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetamide (0.23H2O)::N-(4-acetylphenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy)acetamide

SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccc(OCC(=O)Nc2ccc(cc2)C(C)=O)cc1

InChI Key InChIKey=ZKUCFFYOQOJLGT-UHFFFAOYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50086173   

TargetAdenosine receptor A2b(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086173(N-(4-acetylphenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,...)
Affinity DataKi:  1.39nMAssay Description:Antagonist activity against human A2B adenosine receptor expressed in HEK293 cells uisng [3H]ZM-241385 or [125I]-IABOPXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086173(N-(4-acetylphenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,...)
Affinity DataKi:  1.39nMAssay Description:Antagonist activity against human adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086173(N-(4-acetylphenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]IABOPX to human A2B receptor assessed as inhibition constant by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086173(N-(4-acetylphenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,...)
Affinity DataKi:  37.6nMAssay Description:Antagonist activity against adenosine A1 receptor in rat brain membrane in presence of [3H]R-PIA radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086173(N-(4-acetylphenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,...)
Affinity DataKi:  112nMAssay Description:Antagonist activity against recombinant human adenosine A2A receptor expressed in HEK293 cells in presence of [125I]iodo-ZM-241385 radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086173(N-(4-acetylphenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,...)
Affinity DataKi:  112nMAssay Description:Antagonist activity against human adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086173(N-(4-acetylphenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,...)
Affinity DataKi:  157nMAssay Description:Antagonist activity against recombinant human adenosine A1 receptor expressed in HEK293 cells in presence of [125I]IABA radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086173(N-(4-acetylphenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,...)
Affinity DataKi:  157nMAssay Description:Antagonist activity against human adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086173(N-(4-acetylphenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,...)
Affinity DataKi:  230nMAssay Description:Antagonist activity against human adenosine A3 receptor expressed in HEK cells in presence of [125]IAB-MECA or [125I]IABA radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086173(N-(4-acetylphenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,...)
Affinity DataKi:  230nMAssay Description:Antagonist activity against human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086173(N-(4-acetylphenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,...)
Affinity DataKi:  548nMAssay Description:Antagonist activity against adenosine A2A receptor in rat striatal membrane in presence of [3H]CGS-21680 radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed