BDBM50086103 8-Fluoro-1,3,4,5-tetrahydro-pyrido[4,3-b]indole-2-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide::CHEMBL15808

SMILES COc1ccc(NC(=O)N2CCc3[nH]c4ccc(F)cc4c3C2)cc1N1CCN(C)CC1

InChI Key InChIKey=OKAPXVXSORGNAI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50086103   

Target5-hydroxytryptamine receptor 1B(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50086103(8-Fluoro-1,3,4,5-tetrahydro-pyrido[4,3-b]indole-2-...)
Affinity DataIC50: 567nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50086103(8-Fluoro-1,3,4,5-tetrahydro-pyrido[4,3-b]indole-2-...)
Affinity DataIC50: 667nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1D receptor in rat frontal cortex using [125I]iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50086103(8-Fluoro-1,3,4,5-tetrahydro-pyrido[4,3-b]indole-2-...)
Affinity DataIC50: 800nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex using [125I]iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed