BDBM50086101 4-[4-(5-Fluoro-1H-indol-3-yl)-butyl]-piperazine-1-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide::CHEMBL15837

SMILES COc1ccc(NC(=O)N2CCN(CCCCc3c[nH]c4ccc(F)cc34)CC2)cc1N1CCN(C)CC1

InChI Key InChIKey=RXGJIWBUJGUKEZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50086101   

Target5-hydroxytryptamine receptor 1B(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50086101(4-[4-(5-Fluoro-1H-indol-3-yl)-butyl]-piperazine-1-...)
Affinity DataIC50: 77nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50086101(4-[4-(5-Fluoro-1H-indol-3-yl)-butyl]-piperazine-1-...)
Affinity DataIC50: 50nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex using [125I]iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50086101(4-[4-(5-Fluoro-1H-indol-3-yl)-butyl]-piperazine-1-...)
Affinity DataIC50: 367nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1D receptor in rat frontal cortex using [125I]iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed