BDBM50086100 4-(5-Cyano-1H-indol-3-yl)-piperidine-1-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide::CHEMBL430122

SMILES COc1ccc(NC(=O)N2CCC(CC2)c2c[nH]c3ccc(cc23)C#N)cc1N1CCN(C)CC1

InChI Key InChIKey=GJIIWFJJJBJFMX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50086100   

Target5-hydroxytryptamine receptor 1D(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50086100(4-(5-Cyano-1H-indol-3-yl)-piperidine-1-carboxylic ...)
Affinity DataIC50: 400nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1D receptor in rat frontal cortex using [125I]iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50086100(4-(5-Cyano-1H-indol-3-yl)-piperidine-1-carboxylic ...)
Affinity DataIC50: 233nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex using [125I]iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50086100(4-(5-Cyano-1H-indol-3-yl)-piperidine-1-carboxylic ...)
Affinity DataIC50: 267nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed