BDBM50085948 2-(3-{3-[5-Phenyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethoxy]-phenyl}-but-2-enyl)-[1,2,4]oxadiazolidine-3,5-dione::CHEMBL7048

SMILES C\C(=C/Cn1oc(=O)[nH]c1=O)c1cccc(OCc2nc(oc2-c2ccccc2)-c2ccc(cc2)C(F)(F)F)c1

InChI Key InChIKey=XBMXYHRZRAJSKO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085948   

TargetTyrosine-protein phosphatase non-receptor type 1(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50085948(2-(3-{3-[5-Phenyl-2-(4-trifluoromethyl-phenyl)-oxa...)
Affinity DataIC50: 300nMAssay Description:Inhibition of PTPase activity using recombinant r-PTP1B as the enzyme and IR-triphosphopeptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50085948(2-(3-{3-[5-Phenyl-2-(4-trifluoromethyl-phenyl)-oxa...)
Affinity DataIC50: 300nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed