BDBM50085911 7-{(1R,2R,3R,5S)-2-[(R)-4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-dihydroxy-cyclopentyl}-heptanoic acid::7-{2-[4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-dihydroxy-cyclopentyl}-heptanoic acid::CHEMBL36041

SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)COc1cccc(Cl)c1

InChI Key InChIKey=XECZBZWECQIBDA-UHFFFAOYSA-N

Data  9 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50085911   

TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085911(7-{2-[4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-di...)
Affinity DataEC50:  8.00E+3nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human TP-receptor (% of control ligand, [3H]-U-46,619=90%)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085911(7-{2-[4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-di...)
Affinity DataEC50: >2.00E+4nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP3 (% of control ligand, sulprostone<50%)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085911(7-{2-[4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-di...)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGF2-alpha from human FP-receptor expressed in CHO-KI cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085911(7-{2-[4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-di...)
Affinity DataEC50:  1.90E+4nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP1 (% of control ligand, 17-phi-PGE2=100%)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085911(7-{2-[4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-di...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity for Prostaglandin I2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085911(7-{2-[4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-di...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity for Prostanoid TP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085911(7-{2-[4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-di...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity for human Prostaglandin D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085911(7-{2-[4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-di...)
Affinity DataIC50: 3.10E+3nMAssay Description:Affinity for Prostanoid EP3 receptor expressed in CHO cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085911(7-{2-[4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-di...)
Affinity DataIC50: 6.70E+3nMAssay Description:Affinity for Prostanoid EP2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085911(7-{2-[4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-di...)
Affinity DataIC50: 1.36E+3nMAssay Description:Affinity for Prostanoid EP1 receptor expressed in COS-7 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085911(7-{2-[4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-di...)
Affinity DataIC50: 2.60nMAssay Description:Affinity for human Prostanoid FP receptor expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085911(7-{2-[4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-di...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity for Prostanoid EP4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085911(7-{2-[4-(3-Chloro-phenoxy)-3-hydroxy-butyl]-3,5-di...)
Affinity DataEC50:  9nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human FP-receptor (% of control ligand, fluprostenol=100%)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed