BDBM50085702 4-(5-Hydroxymethyl-3-phenyl-isoxazol-4-yl)-benzenesulfonamide::CHEMBL1147::Hydroxylated derivative (metabolite 1)

SMILES NS(=O)(=O)c1ccc(cc1)-c1c(CO)onc1-c1ccccc1

InChI Key InChIKey=UJSFKTUZOASIPA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50085702   

TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50085702(4-(5-Hydroxymethyl-3-phenyl-isoxazol-4-yl)-benzene...)
Affinity DataIC50: 180nMAssay Description:In Vitro activity of compound against human recombinant Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50085702(4-(5-Hydroxymethyl-3-phenyl-isoxazol-4-yl)-benzene...)
Affinity DataIC50: 1.12E+6nMAssay Description:In Vitro activity of compound against human recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50085702(4-(5-Hydroxymethyl-3-phenyl-isoxazol-4-yl)-benzene...)
Affinity DataIC50: 180nMAssay Description:In Vitro activity of compound against human recombinant Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50085702(4-(5-Hydroxymethyl-3-phenyl-isoxazol-4-yl)-benzene...)
Affinity DataIC50: 182nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed