BDBM50085554 5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5')ADENOSINE::CHEMBL414948::Oligoadenylate analogue

SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)O[C@@H]2[C@H](O)[C@@H](COP(O)(=O)O[C@@H]3[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]3n3cnc4c(N)ncnc34)O[C@H]2n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O

InChI Key InChIKey=SIIZPVYVXNXXQG-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50085554   

Target2-5A-dependent ribonuclease(Human)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085554(Oligoadenylate analogue | 5'-O-MONOPHOSPHORYLADENY...)
Affinity DataEC50:  0.200nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Human)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085554(Oligoadenylate analogue | 5'-O-MONOPHOSPHORYLADENY...)
Affinity DataEC50:  0.150nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target2-5A-dependent ribonuclease(Human)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085554(Oligoadenylate analogue | 5'-O-MONOPHOSPHORYLADENY...)
Affinity DataIC50: 7.30nMAssay Description:Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed