BDBM50085524 CHEMBL102578::Cyclic urea 2,4-diazepin-3-one analogue

SMILES NC(=[NH2+])c1cccc(c1)N1CCCCN(C2CCN(CC2)C(=O)Cc2ccccc2)C1=O

InChI Key InChIKey=CIOJDYINTCGHMC-UHFFFAOYSA-O

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085524   

TargetCoagulation factor X(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085524(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL10...)
Affinity DataKi:  900nMAssay Description:Inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085524(Cyclic urea 2,4-diazepin-3-one analogue | CHEMBL10...)
Affinity DataKi:  1.18E+4nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed