BDBM50085459 (S)-3-Biphenyl-4-yl-2-[(S)-3-methyl-2-(phosphonomethyl-amino)-butyrylamino]-propionic acid::CHEMBL89563

SMILES CC(C)[C@H](NCP(O)(O)=O)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(O)=O

InChI Key InChIKey=NVOGZCACYSGYEQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50085459   

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50085459((S)-3-Biphenyl-4-yl-2-[(S)-3-methyl-2-(phosphonome...)
Affinity DataIC50: 3nMAssay Description:In vitro inhibitory concentration against neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetNeprilysin(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085459((S)-3-Biphenyl-4-yl-2-[(S)-3-methyl-2-(phosphonome...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085459((S)-3-Biphenyl-4-yl-2-[(S)-3-methyl-2-(phosphonome...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50085459((S)-3-Biphenyl-4-yl-2-[(S)-3-methyl-2-(phosphonome...)
Affinity DataIC50: 25nMAssay Description:In vitro inhibitory concentration against angiotensin-converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article