BDBM50085413 3-(3,5-dichloro-4-hydroxybenzylidene)-5-phenylindolin-2-one::3-[1-(3,5-Dichloro-4-hydroxy-phenyl)-meth-(Z)-ylidene]-5-phenyl-1,3-dihydro-indol-2-one::CHEMBL73470

SMILES Oc1c(Cl)cc(\C=C2/C(=O)Nc3ccc(cc23)-c2ccccc2)cc1Cl

InChI Key InChIKey=FWRONJFWBOKLJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085413   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50085413(3-[1-(3,5-Dichloro-4-hydroxy-phenyl)-meth-(Z)-ylid...)
Affinity DataIC50: 32nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50085413(3-[1-(3,5-Dichloro-4-hydroxy-phenyl)-meth-(Z)-ylid...)
Affinity DataIC50: 32nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed