BDBM50085401 CHEMBL421676::N-[(E)-3-(5-Carbamimidoyl-2-hydroxy-phenyl)-allyl]-4-(3H-imidazol-4-yl)-benzamide

SMILES NC(=N)c1ccc(O)c(C=CCNC(=O)c2ccc(cc2)-c2c[nH]cn2)c1

InChI Key InChIKey=GHYAMUIQUOQEJY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50085401   

TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085401(N-[(E)-3-(5-Carbamimidoyl-2-hydroxy-phenyl)-allyl]...)
Affinity DataKi:  19nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085401(N-[(E)-3-(5-Carbamimidoyl-2-hydroxy-phenyl)-allyl]...)
Affinity DataKi:  1.80E+3nMAssay Description:In vitro inhibition of trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085401(N-[(E)-3-(5-Carbamimidoyl-2-hydroxy-phenyl)-allyl]...)
Affinity DataKi: >4.00E+3nMAssay Description:In vitro inhibition of coagulation factor IIa.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed