BDBM50085345 CHEMBL60776::N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(4-hydroxy-phenyl)-propionamide

SMILES Oc1ccc(CCC(=O)N[C@@H](Cc2ccccc2)C(=O)CCl)cc1

InChI Key InChIKey=XKAYYQOZIMXLDI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50085345   

TargetCathepsin G(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085345(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(4-hydrox...)
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibitory activity against human leukocyte cathepsin GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085345(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(4-hydrox...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory activity against human serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085345(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(4-hydrox...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory activity against alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin(Pig)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085345(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(4-hydrox...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against porcine pancreatic trypsin (TRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-like elastase family member 2A(Pig)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085345(N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(4-hydrox...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed