BDBM50085301 5-[4-(2-Pyrrolidin-1-yl-ethoxy)-benzyl]-thiazole::CHEMBL349672

SMILES C(CN1CCCC1)Oc1ccc(Cc2cncs2)cc1

InChI Key InChIKey=CUOVSRHGTNJBTE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085301   

TargetLeukotriene A-4 hydrolase(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50085301(5-[4-(2-Pyrrolidin-1-yl-ethoxy)-benzyl]-thiazole |...)
Affinity DataIC50: 77nMAssay Description:Inhibitory activity was determined against Leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50085301(5-[4-(2-Pyrrolidin-1-yl-ethoxy)-benzyl]-thiazole |...)
Affinity DataIC50: 220nMAssay Description:Inhibitory activity was determined for LTB4 production in human whole blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed