BDBM50085266 4-[4-(2-Pyrrolidin-1-yl-ethoxy)-benzyl]-thiazole::CHEMBL165407

SMILES C(CN1CCCC1)Oc1ccc(Cc2cscn2)cc1

InChI Key InChIKey=OQSBOXPXDFAPCA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50085266   

TargetLeukotriene A-4 hydrolase(Human)
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50085266(4-[4-(2-Pyrrolidin-1-yl-ethoxy)-benzyl]-thiazole |...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50085266(4-[4-(2-Pyrrolidin-1-yl-ethoxy)-benzyl]-thiazole |...)
Affinity DataIC50: 240nMAssay Description:Inhibitory activity was determined for LTB4 production in human whole blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Gyeongsang National University (Gnu)

Curated by ChEMBL
LigandPNGBDBM50085266(4-[4-(2-Pyrrolidin-1-yl-ethoxy)-benzyl]-thiazole |...)
Affinity DataIC50: 190nMAssay Description:Inhibitory activity was determined against Leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed