BDBM50085030 Benzyl-((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-methyl-amine::Benzyl-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-methyl-amine::CHEMBL293951

SMILES C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)N(C)Cc1ccccc1

InChI Key InChIKey=OHQXZYAOUKKRAK-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50085030   

TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50085030(Benzyl-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,...)
Affinity DataKi:  44nMAssay Description:Binding affinity was determined against Opioid receptor kappa 1 obtained from guinea pig brain membranes using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50085030(Benzyl-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,...)
Affinity DataKi:  44nMAssay Description:Binding affinity towards Opioid receptor kappa 1 from guinea pig brain using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50085030(Benzyl-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,...)
Affinity DataKi:  56nMAssay Description:Binding affinity was determined against Opioid receptor mu 1 obtained from guinea pig brain membranes using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50085030(Benzyl-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,...)
Affinity DataKi:  56nMAssay Description:Binding affinity towards Opioid receptor mu 1 from guinea pig brain using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50085030(Benzyl-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,...)
Affinity DataKi:  570nMAssay Description:Binding affinity towards Opioid receptor delta 1 from guinea pig brain using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50085030(Benzyl-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,...)
Affinity DataKi:  570nMAssay Description:Binding affinity was determined against Opioid receptor delta 1 obtained from guinea pig brain membranes using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed