BDBM50084775 7-(Quinolin-2-ylmethoxy)-naphthalene-2-carboxylic acid {2-[4-(1H-tetrazol-5-yl)-phenyl]-ethyl}-amide::CHEMBL423333::N-(4-(5H-tetrazol-5-yl)phenethyl)-7-(quinolin-2-ylmethoxy)-2-naphthamide

SMILES O=C(NCCc1ccc(cc1)-c1nnn[nH]1)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1

InChI Key InChIKey=WRUOBLKMAADSPN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50084775   

TargetCysteinyl leukotriene receptor 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50084775(N-(4-(5H-tetrazol-5-yl)phenethyl)-7-(quinolin-2-yl...)
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
Laboratorios Menarini

Curated by ChEMBL
LigandPNGBDBM50084775(N-(4-(5H-tetrazol-5-yl)phenethyl)-7-(quinolin-2-yl...)
Affinity DataKi:  3.40nMAssay Description:In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]LTD4 binding assay in guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed