BDBM50084762 4-(4-Methoxy-benzenesulfonyl)-piperazine-1,3-dicarboxylic acid 1-benzylamide 3-hydroxyamide::4-Benzylthiocarbamoyl-1-(4-methoxy-benzenesulfonyl)-piperazine-2-carboxylic acid hydroxyamide::CHEMBL126388

SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=S)NCc1ccccc1

InChI Key InChIKey=DEZZFUOGAFLCST-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50084762   

TargetMatrix metalloproteinase-9(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084762(4-Benzylthiocarbamoyl-1-(4-methoxy-benzenesulfonyl...)
Affinity DataIC50: 6.60nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084762(4-Benzylthiocarbamoyl-1-(4-methoxy-benzenesulfonyl...)
Affinity DataIC50: 41nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084762(4-Benzylthiocarbamoyl-1-(4-methoxy-benzenesulfonyl...)
Affinity DataIC50: 401nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084762(4-Benzylthiocarbamoyl-1-(4-methoxy-benzenesulfonyl...)
Affinity DataIC50: 68nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084762(4-Benzylthiocarbamoyl-1-(4-methoxy-benzenesulfonyl...)
Affinity DataIC50: 41nMAssay Description:Binding affinity towards matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed