BDBM50084727 1-(4-Methoxy-benzenesulfonyl)-4-(4-methyl-[1,2,3]thiadiazole-5-carbonyl)-piperazine-2-carboxylic acid hydroxyamide::CHEMBL338453

SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1snnc1C

InChI Key InChIKey=JZJWCJQEWXNHBE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50084727   

TargetMatrix metalloproteinase-9(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084727(1-(4-Methoxy-benzenesulfonyl)-4-(4-methyl-[1,2,3]t...)
Affinity DataIC50: 17nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084727(1-(4-Methoxy-benzenesulfonyl)-4-(4-methyl-[1,2,3]t...)
Affinity DataIC50: 21nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084727(1-(4-Methoxy-benzenesulfonyl)-4-(4-methyl-[1,2,3]t...)
Affinity DataIC50: 173nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084727(1-(4-Methoxy-benzenesulfonyl)-4-(4-methyl-[1,2,3]t...)
Affinity DataIC50: 1.06E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084727(1-(4-Methoxy-benzenesulfonyl)-4-(4-methyl-[1,2,3]t...)
Affinity DataIC50: 6.09E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084727(1-(4-Methoxy-benzenesulfonyl)-4-(4-methyl-[1,2,3]t...)
Affinity DataIC50: 173nMAssay Description:Binding affinity towards matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed