BDBM50084722 (4-Hydroxy-1-methyl-4-phenyl-piperidin-3-yl)-phenyl-methanone::CHEMBL122360

SMILES CN1CCC(O)(C(C1)C(=O)c1ccccc1)c1ccccc1

InChI Key InChIKey=TVRFABREAYQAQA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50084722   

TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084722((4-Hydroxy-1-methyl-4-phenyl-piperidin-3-yl)-pheny...)
Affinity DataKi:  2.59E+3nMAssay Description:Inhibition of [3H]DA Uptake at Dopamine transporter in rat cortex was measured by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50084722((4-Hydroxy-1-methyl-4-phenyl-piperidin-3-yl)-pheny...)
Affinity DataKi:  4.42E+3nMAssay Description:Binding Affinity to cocaine site of Dopamine transporter in caudate nuclei which was homogenized and incubated with [3H]mazindol. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed