BDBM50084659 3-Bromo-5-chloro-N-[5-chloro-2-(1-chloro-naphthalen-2-yloxy)-phenyl]-2-hydroxy-benzamide::CHEMBL115114

SMILES Oc1c(Br)cc(Cl)cc1C(=O)Nc1cc(Cl)ccc1Oc1ccc2ccccc2c1Cl

InChI Key InChIKey=UICKPIYIRFGAGL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084659   

TargetPoly(ADP-ribose) glycohydrolase(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50084659(3-Bromo-5-chloro-N-[5-chloro-2-(1-chloro-naphthale...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of PARG using [alpha-32P]ADP-ribose polymers after 5 mins by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50084659(3-Bromo-5-chloro-N-[5-chloro-2-(1-chloro-naphthale...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of PARP-1 using [32P]-NAD+ after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50084659(3-Bromo-5-chloro-N-[5-chloro-2-(1-chloro-naphthale...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibitory concentration against ProteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50084659(3-Bromo-5-chloro-N-[5-chloro-2-(1-chloro-naphthale...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibitory concentration against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed