BDBM50084314 CHEMBL56373::N-(7-Hydroxy-2,2,4,6-tetramethyl-indan-1-yl)-2-[4-(3-methoxy-phenyl)-piperazin-1-yl]-acetamide

SMILES COc1cccc(c1)N1CCN(CC(=O)NC2c3c(CC2(C)C)c(C)cc(C)c3O)CC1

InChI Key InChIKey=LYAUICDWKQJAGX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50084314   

TargetSigma non-opioid intracellular receptor 1(Rat)
Otsuka Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50084314(N-(7-Hydroxy-2,2,4,6-tetramethyl-indan-1-yl)-2-[4-...)
Affinity DataIC50: 1.50E+4nMAssay Description:Binding affinity for sigma receptor was evaluated by the inhibitory effect on [3H]DTG to rat whole brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed