BDBM50084301 (S)-2-(4'-fluoro-biphenyl-4-sulfonylamino)-3-methyl-butyric acid::2-(4'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-butyric acid::CHEMBL418442

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(F)cc1)C(O)=O

InChI Key InChIKey=INVXSBCIDABVMG-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50084301   

TargetMatrix metalloproteinase-9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50084301(2-(4'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50084301(2-(4'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50: 10nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50084301(2-(4'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50: 43nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50084301(2-(4'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50084301(2-(4'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50084301(2-(4'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50084301(2-(4'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50: 4.80E+3nMAssay Description:In vitro inhibition of matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50084301(2-(4'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50: 6.40E+4nMAssay Description:In vitro inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50084301(2-(4'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50: 4.20E+3nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50084301(2-(4'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50: 39nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50084301(2-(4'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50084301(2-(4'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50: 43nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50084301(2-(4'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50: 6.46E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed