BDBM50084262 CHEMBL3425963

SMILES FC(F)(F)CN1CCC(CC1)NC(=O)c1ccc(nc1)N1CCOCC1

InChI Key InChIKey=XUBULEBZIIMPFC-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50084262   

TargetHematopoietic prostaglandin D synthase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50084262(CHEMBL3425963)
Affinity DataKd:  400nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50084262(CHEMBL3425963)
Affinity DataIC50: 320nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed